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A 2020 study found NAC improved dopaminergic function in PD patients

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However, they reported notable improvements in clinician-rated assessments, with patients ages 315 years of age showing significant improvement in the sulforaphane treatment group on the OSU Autism rating scale DSM-IV (OARS-4) in particular (Ou et al., 2024)

Overall, apathy is correlated with more cortical amyloid burden (Marshall et al., 2013