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Increased iron absorption, lipid peroxidation, and the buildup of lipid peroxides, which results in cell death, are the hallmarks of the process

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The conversation highlights the strong bidirectional relationship between insulin resistance and thyroid dysfunction, including how each can worsen the other when left unaddressed

DFO administration not only attenuated the STEAP3 knockdown-induced Fe accumulation but also concomitantly rescued mitochondrial bioenergetics and mitigated intracellular lipid peroxide formation (Supplementary Fig