Catalpol Attenuates hepatic steatosis by regulating lipid metabolism via AMP-activated protein kinase activation
The protective mechanisms of catalpol primarily involve its anti-inflammatory, antioxidative stress, anti- or pro-apoptotic, anti-fibrotic, metabolism-regulatory, anti-endoplasmic reticulum stress (ERS), and pyroptosis-modulating functions
Patients dying with dementia: Experience at the end of life and impact of hospice care
This peptide, consisting of 28 amino acids, is widely distributed in the nervous system and acts as a neurotransmitter, neuromodulator, and vasodilator
PGC-1, a pivotal regulator of mitochondrial biogenesis and cellular resistance to oxidative stress, plays a pivotal role in the function and survival of dopaminergic neurons in the substantia nigra (Halling and Pilegaard, 2020)
In trials, it outperformed 3% Minoxidil in density metrics