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A triple combination of targeting ligands increases the penetration of nanoparticles across a bloodbrain barrier culture model

Samples were scanned in 10 different areas (microscope JEOL JCM-6000

Data suggests that the combination therapy results in a smoother, more sustained reduction in gastric emptying compared to monotherapy, leading to a more stable blunting of post-prandial glucose spikes without the compensatory hypoglycaemia often seen in insulin-based interventions

It remains an investigational compound in Phase 3 clinical development