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Lancet 2021 Phase 2 (monotherapy) Lau et al., n=706, 26 weeks

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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Calanna S., Christensen M., Holst J.J., et al

The variable weight value (VIP) in Orthogonal Partial Least Squares-Discriminant Analysis is a measure of the expression pattern of each metabolite, the explanatory ability and depth of influence on the categorical discrimination of samples in each group, to explore meaningful differential metabolites, and then use the T-test to verify whether the differential metabolites between groups are significant

DEFINITION 05 Certificate of Analysis (CoA) A document issued by the manufacturer or testing laboratory that verifies the identity, purity, and concentration of a specific production lot