Taken together, our data suggested an obvious reduction in carnitine bioavailability in individuals with higher TMAO productivity, probably because a considerable portion of ingested carnitine was consumed and converted to TMA by the gut microbiota (Fig
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As one of the risk factors, obesity has a role in OA, including increased joint loads, altered metabolism, and low-grade inflammation [33]
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Toxicol Appl Pharmacol 231:336343
Carnitine supplementation helps normalize this electrical signal, significantly reducing the risk of sudden cardiac arrest [10] [11]