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Findings indicate elevated oxidative stress markers (MDA, 4-HNE), impaired antioxidant defenses [CoQ10 (Coenzyme Q10), SOD, catalase], and mitochondrial dysfunction in FM patients
This results in an overproduction of pro-inflammatory cytokines such as interleukin 6 (IL-6), tumour necrosis factor , adhesion molecules, prostaglandins, and mitogen-activated protein kinase signalling cascades
(11) Dawi J, Misakyan Y, Affa S, Kades S, Narasimhan A, Hajjar F, Besser M, Tumanyan K, Venketaraman V
The first requirement is to generate ribose 5-phosphate for the synthesis of nucleotides, and the other is to provide reducing power in the form of NADPH
Gastrointestinal Health Due to its origin from gastric proteins, this peptide shows promise in addressing digestive system disorders