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Inhibition of Mrp2- and Ycf1p-mediated transport by reducing agents: Evidence for GSH transport on rat Mrp

The peptide has a very short plasma half-life of approximately 3 minutes, which influences dosing frequency and timing considerations

Kaidbey et al

BMC Bioinformatics 4 , 41 (2003)

N-acetylprocainamide is an acetylated form of procainamide, thus examples of Phase II metabolism) Most Phase II metabolism yields metabolites that are polar with poor properties for bioavailability after oral administration

The fifteen amino acids of penta deca peptide arginate represent one of the clearest examples of this principle in modern peptide research