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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimers disease

This results in defects in mitophagy, whereas a large number of dysfunctional mitochondria are not removed in time and excessively accumulate in neuronal cells, which induces a vicious circle-chain reaction (Wong and Holzbaur, 2014)

Further research revealed its inhibitory effect on tyrosinase, an enzyme involved in melanin production, which highlighted its potential for hyperpigmentation and uneven tone

doi: 10.1111/pme.12853 53

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Ashok Shetty, university distinguished professor and associate director of the Institute for Regenerative Medicine, along with senior research scientists Dr