In addition to using genetically engineered bacteria as drug delivery carriers, extracellular vesicles (EVs), especially exocrine bodies, originate from cells through exocytosis and are absorbed by target cells, which can transmit biological signals or even deliver drugs between local or distant cells (47)
Based on the collective clinical evidence, daily oral doses of approximately 2.55 g appear to be the most consistently effective, whereas higher intakes (e.g., up to 10 g/day) have not consistently shown proportionally greater benefits and may not be necessary for skin-related outcomes [93]
Umeno A, Biju V, Yoshida Y
Recombinant human insulin-like growth factor-I enhances whole body protein anabolism and significantly diminishes the protein catabolic effects of prednisone in humans without a diabetogenic effect
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