The main nutrients required for methylation are B vitamins, particularly B6, B9 (folate) and B12
The idea that oxidative stress plays a role in the pathophysiology of ADHD is also consistent with meta-analysis results finding low levels of zinc in patients with ADHD (Scassellati, Bonvicini, Faraone, & Gennarelli, 2012), because zinc is a cofactor in many reactions that promote antioxidant defenses (Jomova & Valko, 2011)
Plays role in maintaining skin health
Vitamin B12 created through fermentation Like many vitamins, Vitamin B12 is usually sourced from animals - but not ours
This protease-driven nerve activation is now believed to be a major contributor to the visceral hypersensitivity and widespread "nociplastic" pain seen in conditions like irritable bowel syndrome (IBS), ME/CFS, and fibromyalgia
2013;8:e56625