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Neptun showed an increased expression of glutathione transferase StGSTF2 and a general activity of GST, corresponding with an increase in the GSSG form and indicating involvement in the resistance reaction

Cancer-associated fibroblasts in colorectal cancer

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Glutathione-Related Enzymes and Proteins: A Review

DarleyUsmar and coworkers have shown that HNE directly modifies Keap1, which allows Nrf2 to avoid degradation and migrate to the nucleus where it can bind to EpRE elements in the promoters of the human GCLC and GCLM genes (Levonen et al., 2004)

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