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All of these factors can contribute to poor production of glutathione (or of the enzymes that help glutathione to do its work), and many also deplete the GSH that the cells produce (by converting it into GSSG)

doi: 10.1038/s41573-018-0008-x 50 CunhaL

Supports collagen for anti-ageing benefits 5

Int J Epidemiol

Additionally, one clinical study reported that consumption of chlorogenic acid-enriched coffee not only improved plasma antioxidant capacity and decreased plasma lipid and protein oxidation but also donated to enhancing cardiovascular health in people with hypercholesterolemia [169]

Vascular ROS can be produced in both endothelium and smooth muscle