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The coprimary end points were the relative change in body weight and a reduction of greater than or equal to 5% in body weight from baseline to week 68 with cagrilintide plus semaglutide compared with placebo

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Noticed meaningful improvement around week 2

Because both delta sleep and GH secretion peak concurrently in the early night, DSIP's sleep-deepening effects and GH-modulating effects may represent two manifestations of the same underlying neuroendocrine circuit restoration