Furthermore, GPER enhances insulin responsiveness in adipose tissue, suppresses hepatic glucose production, and reduces blood glucose levels, further augmenting insulin sensitivity [4, 31]
(Side-effects prompted almost twenty-five percent of FM patients to drop out of one study.) Reduced Synergy = Reduced Results
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Food Chem 185:389397 Smith H, Doyle S, Murphy R (2023) Target directed identification of natural bioactive compounds from filamentous fungi
For example, bioavailability is particularly low for flavones, while it is higher for flavanones and soy isoflavones