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GPX4 requires GSH as a cofactor to inhibit lipid peroxidation, and GPX4 has gained research momentum because of its important role in maintaining spermatogenesis [77]

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A primary biological role of AAT is maintenance of the normal protease-antiprotease balance (53)

In conclusion, our data suggest that GSSG is a potent and clinically relevant sensitizer for TNF-induced hepatotoxicity in NAFLD, which represents a potential therapeutic target for NAFLD

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