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We stimulated the 5-LOX pathway using calcium ionophore A23187, and used LC-MS/MS to detect the formation of major eicosanoids derived from AA

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doi: 10.1194/jlr.R800035-JLR200 14 LiaoPWangWWangWKryczekILiXBianYet al

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Ann Intern Med 125:384389 Rishavy MA, Hallgren KW, Wilson LA, Usubalieva A, Runge KW, Berkner KL (2013) The vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylation