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The peptide demonstrates ability to reduce production of pro-inflammatory cytokines including tumor necrosis factor-alpha (TNF-) and interleukin-1 beta (IL-1), while promoting anti-inflammatory responses

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Dihexa was designed by researchers at Washington State University as a metabolically stable analog of Angiotensin IV

KEY POINTS Oxidative stress occurs when there is an imbalance between the production of reactive oxygen species (ROS) and their clearance by antioxidants

Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin

However, leukocyte activation, regulation of activation and positive regulation of immune response were associated with genes in the blue module ( Figure 4E )