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Moreover, about 3-fold slower CL and 3-fold longer MRT were calculated for the QMP-engineered fusions compared to GLP-1 WT (Supplementary Table 4)

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Furthermore, secretion of 27HC by hepatocellular carcinoma cells enhances lipid metabolism in macrophages and activates peroxisome proliferator-activated receptor- (PPAR) signaling, driving M2-type macrophage polarization (39)