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Similarly, doxorubicin was identified as a promising drug candidate for on-chip testing, because of the large IC 50 difference between KISPIDMG-105, SF8628, and the BBB (IC 50 = 0.30 M, 0.86 M and 7.04 M, respectively), which indicated a potentially safe therapeutic window

J.MoylanS.O'NeilA.et al (2013)

Partial least squares-discriminant analysis (PLS-DA) of metabolite concentrations discriminated between lupus and control PBL (Fig

Mol Cancer Res 16:10731076 Lee DH, Park JS, Lee YS, Han J, Lee DK, Kwon SW, Han DH, Lee YH, Bae SH (2020a) Sqstm1/p62 activates nfe2l2/nrf2 via ulk1-mediated autophagic keap1 degradation and protects mouse liver from lipotoxicity

Research published in Biochemical Pharmacology demonstrates GHK-Cu activating integrin signaling, upregulating nerve growth factor (NGF), and engaging decorin pathways that organize newly synthesized collagen into functional extracellular matrix architecture

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