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MDA can form adducts by reacting with proteins and DNA, thereby disrupting cellular functions and potentially inducing mutations in genetic material [131]

Phase Cag introduction Weeks 9-12 Tirzepatide 5.0 mg/week (hold) Cagrilintide 0.25 mg/week Notes Add cagrilintide at the lowest dose

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Groisman, G

Peptide cost calculations reveal that storage-related degradation represents a significant expense category

Evidence quality: Mechanistic (human) + Phase II exploratory