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Future research could further explore the combination of CUL5-knockout CAR-NK cells with other immunotherapeutics, such as PD-1/PD-L1 inhibitors, to potentially amplify the anti-tumor response

Tumor microenvironment and its role in cancer progression: an integrative review

Peroxisome proliferatoractivated receptor (PPAR), a crucial transcriptional factor, regulates FAO via controlling the transcription and translation of FAO-related enzymes (Xu et al., 2022), which could further trigger the impairment of mitochondrial structure and function ( 3 Natural products for regulating mitochondrial function 3.1 Enhancing mitochondrial biogenesis and energetics It is widely found that impaired mitochondrial biogenesis and energetics contribute to the pathogenesis of kidney diseases (Weinberg, 2011

doi: 10.1159/000523766

The application requires understanding that peptides are not symptom treatments

The technique matters as much as the materials