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Governments regulate e-cigarettes by prohibiting their sale, permitting their sale only as licensed medicinal products, or by applying certain supply and demand reduction measures consistent with those outlined in the WHO Framework Convention on Tobacco Control (WHO FCTC)

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It therefore appears that to be truly effective in terms of harm reduction, e-cigarettes must be a substitute for tobacco and not simply a complement, for example to obtain a dose of nicotine when smoking cigarettes is not possible