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In experimental models of SCI, this protein has been found to be significantly elevated for up to 11 months in sensory axons, neurons, astrocytes, and ependymal cells, despite consequent loss of nerve tissue at the site of injury

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Glutamate is then catalyzed by glutamate dehydrogenase (GDH) or glutamate transaminase, or aspartate transaminase (TAs) to produce -ketoglutarate (-KG)

Moskovtsev SI, Willis J, Mullen JB