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Metallomics: Integrated Biometal Science , 16

The goal is to isolate the peptide effect from background variability

Reports across the 1980s described DSIP modulation of responses to morphine, amphetamine and barbiturates in rodents, with a profile generally interpreted as opioid-system modulation rather than direct opioid-receptor binding (Graf & Kastin, 1984)

Why is peptide purity so important in this discussion

Ethics Approval and Consent to Participate The original study/trial was previously performed in accordance with the ethical principles of the Declaration of Helsinki and its subsequent amendments (Clinicaltrials.gov identifier NCT01941160) as described in Evans et al