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Supplementary Materials Data Availability Statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author/s.

Non-small cell lung cancer (NSCLC) accounts for 85% of cases of lung cancer, of which lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) are the most common subtypes

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Semaglutide: single receptor, proven pathway Semaglutide is a GLP-1 receptor agonist

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The MGBA represents a dynamic modulator, where microbiota can influence the host's pathophysiological responses to RT