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Research community protocols typically restrict dosing to the morning

Frequency depends on your health goals and provider guidance

NICE guidelines recommend hydroxocobalamin 1 mg intramuscularly three times weekly for 2 weeks (without neurological involvement) or on alternate days until no further improvement (with neurological symptoms)

At 12mg, you need more than one vial per week

B12 is one piece of the energy puzzle This is worth saying clearly: B12 matters, but it's not the whole story

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