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Support for the free radical theory of aging has also been forthcoming from clinical studies in accelerated aging diseases such as Downs syndrome, progeriaboth adult (Werners syndrome) and childhood (HutchisonGilford)

Reduced spontaneous colonic motor activity by up to 40% in vitro models

32 also reported that antioxidant activities involving SOD, CAT, GR and APX were reduced under abiotic treatment while the application of GSH enhanced their activity

Reconstituted solution or liposomal suspension subjected to the same exposure is likely compromised

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Functional studies (Shelton and McCarthy, 1999