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Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection

A systematic rotation schedule alternating between abdomen quadrants, left and right thighs, and arms ensures no site receives repeated injections within 24 to 48 hours

GABA is an inhibitory neurotransmitter that relies on vitamin B6 as a cofactor for biosynthesis.[ref] Related article: GABA: Genetics, Anxiety, and Immune Response Genetic mutations in the PDXK gene, which converts pyridoxine from food into the active P5P form, can cause peripheral polyneuropathy.[ref] Thus, a safer option for someone with peripheral neuropathy may be to supplement with the active P5P form of vitamin B6

These come in various sizes, but 0.5ml or 1ml syringes with 29 to 31 gauge needles work well for subcutaneous administration

The differences in frequency between genotypes are not statistically significant (p=0.433, Fishers Exact test)

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