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CLIA stands for Clinical Laboratory Improvement Amendments and is the result of a 1988 congressional amendment that created quality and reliability standards for laboratories

Transient and mostly mild-to-moderate gastrointestinal symptoms were the most frequently reported AE and occurred more frequently with the 4 mg starting dose groups rather than the 2 mg starting dose groups [67]

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Srinivas US, Tan BWQ, Vellayappan BA, Jeyasekharan AD

It could mean anything from a simple infection to something serious like kidney stones or bladder cancer

"FDA Sends Warning Letters to Seven Companies Illegally Selling Hangover Products"