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The concentration of MDA and 4-HNE was detected using lipid peroxidation (MDA) Assay kit (abcam, USA) and lipid peroxidation (4-HNE) Assay kit (abcam, USA) according to the manufacturer's instructions

Although the overall extent of homology with TRPV5 is quite close, it is still necessary to distinguish the separate localizations of both proteins

Clinical observations and research studies provide insight into typical response patterns, though individual results vary significantly based on factors including baseline skin tone, dosage, frequency of administration, and overall health status

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