P.KesharwaniA.DattaS.PrasanthD
doi: 10.1002/ptr.7130 107 LiRCaiLTangWJLeiCHuCMYuF
TSPO is an important regulator of stress responses (ROS and cell death) and mitochondrial dysfunction involved in neurodegenerative diseases, as well as mental and stress-related disorders such as autism spectrum disorder, bipolar disorder, and depression
Neurodevelopmental disorder-associated SNIP1 mutation E366G reduces binding to P-SF3B1 A homozygous SNIP1 mutation (E366G) found in ~ 35 individuals from the Amish population has been identified as the genetic cause of a neurodevelopmental disorder characterized by hypotonia, craniofacial abnormalities, and seizures (NEDHCS) 47,48
Glutathione is an intracellular antioxidant that supports liver detoxification and reduces oxidative stress, but it has no direct effect on appetite, gastric emptying, or metabolic hormone signaling
Baseline serum HO-1 was higher in the honeycomb progression ( +) group than in the honeycomb progression () group (34.2 [21.153.0] ng/mL and 18.5 [7.025.7] ng/mL, respectively)
