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Moreover, PGC-1 is involved in autophagy [47, 48], and may regulate mitophagy by the PINK1-Parkin dependent [49, 50] and independent pathways [51, 52]

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Figure 3 ) stimulates dendritic spine numbers and size, as well as overall dendritic arborization, suggesting a plausible mechanism for enhanced synaptic plasticity, connectivity among neurons, and facilitation of memory [37]

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