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Description

Seventeen gene fragments of GST isozymes ( GSTALX1 , GSTA2 , GSTA2X , GSTAL2X , GSTA3 , GSTAL3 , GSTAL3X1 , GSTA4 , GSTA4LX1 , GSTM2 , GSTK1 , GSTO2 , GSTT1 , GSTZ1X1 , GSTZ1-1 and GST1-2 ) were obtained through polymerase chain reaction (PCR) using the relative primers (Additional file 1: Table S1) with homology arm

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For simvastatin acid there was a 15% decrease in AUCinf and 1% decrease in Cmax [see Drug Interactions (7.1)]

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