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Therapy with BPC-157 peptide allows reversing adverse disease effects caused by local anesthetic abuse

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Longer-lasting changes in cortical levels of the inducible isoform of nitric oxide synthase (iNOS) were observed by immunostaining 3 to 7 days following adult concussive fluid percussion injury (Wada et al., 1998)

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These metabolic changes lead to glomerular hyperfiltration, enlargement, and increased proximal tubular glucose reabsorption via sodium-glucose cotransporter 2, resulting in elevated intraglomerular pressure and hyperfiltration [25]

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