A 2024 systematic review in HSS Journal examined 36 studies published between 1993 and 2024 and reported improved functional, structural, and biomechanical outcomes across muscle, tendon, ligament, and bone injury models in animals
long-term safety and efficacy in humans have not been fully established
Additionally, DSIP has a relatively short half life in human plasma, typically around 7 to 8 minutes, which is important to consider when planning administration timing
Side-by-side comparisons over several months reveal changes that day-to-day observation misses
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Geriatr Nursing 2023;51:209214