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The daily volume of urine excreted, its specific gravity and the concentration of C and AL in it were also determined

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Malvindi MA, Di Corato R, Curcio A, Melisi D, Rimoli MG, Tortiglione C, et al

Accordingly, SARS-CoV-2 infection could inflict direct cytopathic injury to gut epithelia and elicit indirect immune-mediated damage to endothelial cells 252

Fast forward over 270 years, and were still using that same logic to solve everything from the common cold to chronic diseases