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The peptide itself was first identified in human plasma in the early 1970s, and the copper-bound form was recognized shortly afterward as the biologically relevant species in many of the contexts where the tripeptide's activity was characterized

De novo-designed transmembrane domains tune engineered receptor functions

Autophagy is a phagocytic degradation process whose deregulation may contribute to neuronal cell death and is involved in the mechanisms of pathologic conditions, such as cerebral ischemia (Galluzzi et al., 2016

A basic review on estrogen receptor signaling pathways in breast cancer

It removes an inhibitor (CXXC5), allowing the existing pathway to function normally

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