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Clinically used small molecule drugs of ROCK signaling Netarsudil (N) and Wnt signaling LY2090314 (L) were also tested

Even with excellent clinical trial safety data, individual responses may vary

MTF1 is a transcriptional regulator of cellular adaptation to heavy metals that activates the transcription of metallothionein (MT), a copper-binding protein, by binding to a metal response element in the MT promoter [47]

Since then they have been the subject of great interest and study

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Researchers considering this stack should start with conservative doses of each compound and monitor carefully for unexpected effects