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C., Swirski, F

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In controlled trials, facial creams containing GHK-Cu outperformed vitamin C and retinoic acid creams in improving skin quality metrics

Below pH 4.5, proton competition at the histidine nitrogen weakens copper binding

If there is presence of enzymatic activity and/or spontaneous oxidation in storage, we would expect to observe lower levels of total GSH and free GSH, and elevated levels of GSSG, in the EDTA-treated sample stored at 4 o C compared to the non-deproteinized EDTA-treated plasma stored at 80 o C