It is widely available through licensed pharmaceutical suppliers and is the diluent most commonly specified in UK trial protocols and compounding guidance from the Specialist Pharmacy Service (SPS)
Increased generation of reactive oxygen species (ROS) when the heart muscle's oxygen supply is restored (reperfusion) might be an important contributor to myocardial damage occurring during ischemia-reperfusion (36)
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Cadmium can also accumulate in the thyroid gland, resulting in damage to thyroid tissues with chronic exposure
10.1038/s41390-023-02628-9 149