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2 Materials and methods 2.1 Protocol and registration This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement (Moher et al., 2009) and the guidelines from the Cochrane Handbook for Systematic Reviews of Interventions (Higgins and Green, 2008)

Inositol helps establish healthy cell membranes, which facilitate nerve impulses

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The peptide enters the subcutaneous space and reaches systemic circulation without luminal degradation

Animal studies show benefit in colitis, stomach ulcer, and intestinal anastomosis models with oral or intragastric administration