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Vitamin E promotes the strengthening of endogenous antioxidant defences and can protect the pancreas, kidneys, eyes and nervous system in animal models from oxidative stress (Pazdro and Burgess, 2010)

No significant differences were found in the insula or the visual cortex

Lei G, Zhuang L, Gan B

2.1% (consistent with weight loss rate) No Safety Signals: No increased risk of pancreatitis, thyroid tumors, or major CV events Historic Achievement: REDEFINE-1 demonstrated that CagriSema produces the highest mean weight loss (22.7%) ever reported for an obesity pharmacotherapy in a Phase 3 trial

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