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Research Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models Mu X, Qu L, Yin L, Wang L, Liu X, Liu D (2024, October) This study developed a novel fusion peptide, DSIP-CBBBP, combining delta sleep-inducing peptide (DSIP) with a blood-brain barrier crossing peptide, produced via Pichia pastoris
A volume of internal standard (Nle 1 -AngIV, 100 g/mL) equal to 0.1 times the sample serum volume was added
LNPs, which encapsulate siRNA within lipid bilayers, have received the most attention from researchers (93) owing to the fact that they have the ability to protect siRNA and facilitate efficient endosomal escape (94)
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