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Dihexa, with its combined N-hexanoic-Tyr-Ile-(6) aminohexanoic amide structure, exhibited a significantly extended half-life of 335.5 9.5 min, confirming that both N- and C-terminal modifications are effective strategies for improving metabolic stability [1]

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Exp Ther Med 16(1):445451 Yang X, Zhang H, Wu J et al (2018) Humanin attenuates NMDA-induced excitotoxicity by inhibiting ROS-dependent JNK/p38 MAPK pathway [J]

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Immunotoxicol 2013, 10 (3), 292301