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In one example, GSH-driven nanoparticle disintegration releases indomethacin to inhibit PTGS2 while reducing Pt 4 + to cytotoxic Pt 2 + , thereby amplifying cisplatin-induced pyroptosis in pancreatic cancer 218

Ann Agric Environ Med 27(2):184193

As evident from the above discussions, researchers have mostly correlated the cellular radiosensitivity with the GPx activity level which is majorly contributed by GPx1 (because of its higher abundance) [1, 8, 9]