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Via high-butyrate diet intervention and adoptive transfer experiments, it confirmed that a high-butyrate diet can induce the differentiation of follicular Tregs through HDAC inhibition, suppress the production of type II collagen (CII)-specific autoantibodies, and reduce joint swelling and bone erosion

[DOI] [PubMed] [Google Scholar] 69.Perron N.R., Brumaghim J.L

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Clin Pharmacokinet 2017;56:81523

Nature 462 , 739744 (2009)