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As with any innovative therapy, we emphasize a cautious, evidence-informed approach

Popov, 2020

Both preclinical and clinical studies show that circadian disruption aggravates BBB injury, characterized by reduced expression of tight junction proteins (ZO-1, occludin, claudin-5), heightened neuroinflammation (TNF-, IL-1), MMP-9/2mediated extracellular matrix degradation, and HPA axis dysregulation

Using a collagen gel contraction assay, we observed that primary fibroblasts from the lungs of aged GHK-treated mice exhibited enhanced contraction compared to fibroblasts from placebo-treated mice (Figure 4), further supporting the hypothesis that GHK promotes the resolution of collagen scars

Therapeutic concentration persists for 34 days post-dose, which is why twice-weekly protocols maintain continuous tissue regeneration signaling without daily administration

It also affects the same person differently on different occasions