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While mild side effects have been observed, these have not demonstrated a serious risk to patient health

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The clinical data to confirm this in humans simply does not yet exist at the level of phase II or III trials, though early human safety data from trials in inflammatory bowel disease have been encouraging

A review on antibacterial silk fibroin-based biomaterials: current state and prospects

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Red blood cell and endothelial eNOS independently regulate circulating nitric oxide metabolites and blood pressure