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ACTH adrenocorticotropic hormone AD Alzheimer's disease ALLO allopregnanolone AMPA -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid ANT adenine nucleotide transporter protein BBB blood-brain barrier BNST bed nucleus of the stria terminalis CB1 cannabinoid receptor 1 CICR Ca 2+ -induced Ca 2+ release CNS central nervous system DA dopamine DAT dopamine transporter DAT KO dopamine transporter knockout DHEA dehydroepiandrosterone DHEAS dehydroepiandrosterone sulfate GABA gamma-aminobutyric acid GAD generalized anxiety disorder GLIC Gloeobacter ligand-gated ion channels GnRH gonadotrophin-releasing hormone HPA axis hypothalamic-pituitary-adrenal axis HRSA Hamilton Rating Scale for Anxiety IL-6 interleukin-6 L-Type VGCC L-type voltage-gated Ca 2+ channel LTD long-term depression LTP long-term potentiation MCI mild cognitive impairment NMDA N-methyl-D-aspartate OATPs organic anion transporting peptides ORAI1 Ca 2+ release-activated Ca 2+ channel protein 1 PAHS pregnanolone hemisuccinate pCREB phosphorylated CREB PET positron emission tomography PCOS polycystic ovary syndrome PREG pregnenolone PregS pregnenolone sulfate PTSD post-traumatic stress disorder PV parvalbumin PXR pregnane xenobiotic receptor P450 scc cytochrome P450 side chain cleavage sEPSC spontaneous excitatory post-synaptic currents 5-HT serotonin SSRIs selective serotonin reuptake inhibitors StAR protein steroidogenic acute regulatory protein STIM1 stromal interaction molecule 1 THDOC tetrahydrodeoxycorticosterone TRH thyrotropin-releasing hormone TRP channels transient receptor potential channels TSPO translocator protein VDAC voltage-dependent anion channel
The most common research areas linked to Epithalon include longevity studies, cellular aging research, telomere research, sleep-related aging pathways, immune function studies, and overall cellular health investigations
Finally, phenotypic approaches have been taken to study resistance to environmental or endogenous stressors that are thought to be causative agents for other diseases (e.g
GSH, found in every cell, is one of our bodys most abundant and potent antioxidants, composed of three amino acids: glutamine, cysteine, and glycine
Blair IA
[10], [11] GHK-Cu exhibits promising analgesic and anti-aggressive effects in rat models, particularly in response to pain-induced aggressive-defensive behavior
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